0:00 [Music] all right so let's get into some more science okay i love it some of us love science here which hat is that this one probably not right no i don't think either one likes science i don't think so either yeah slides not very popular simon's gonna keep one of them alive too that's true they both hate science let's wear both of them there you go wow very cool pretty cool uh who here knows how to explain how heart works a heart a human heart how all heart works or hearts how it works blood flows through pumps it out goes the rest of the body you got a bunch of chambers yeah and a story continuous blood flow goes through the heart pumps it up goes all the way up i can tell you what i remember there's four chambers one of them is called aorta or some ████ i forgot yeah and then ventricle we got a bunch of legislative judicial why does eyes get so small when he's trying to remember ████ the one that's pumping
0:50 away is ████ blue or some ████ and then it gets oxidated through the blood so then that one becomes red so half of your body that's where your veins are blue and some of those just blue red you're welcome which kind of like this actually it's blue and red going back and forth which color is the vein you have to cut to diffuse it is it the which one's blue and red is it the vein of the artery veins are blue arteries are red there it is i hope you're right so chicken heart is ████ delicious which is also why they tell you uh if you're scuba diving and you get a cut don't freak out when their blood comes out and it's blue it's because it hasn't touched oxygen over here oh that's crazy a cut it's going to turn red immediately immediately because it's getting oxidized it comes out blue in the water that's nice i don't have any dead blood in the water from myself but whatever any depths like yeah probably probably like way lower where you just can't there's no light probably very little oxygen or something
1:41 don't be surprised if you can't see it don't be surprised it's for sure blue though goes by your blood illuminates it enough so uh the world's first heartless human was able to live without a pulse wow well because they had a pacemaker is that are you this is a story about a marion where there's an icebox i enjoyed that i have an ice box where my heart used to be there it is i love omicron we having no pulse means that they can't tell that your heart's beating but your heart's beating right well that's the thing beating uh in terms of the pulse usually is because it's pumping blood right yep however in this situation i'll get into the details there's no pump uh in order to make the blood flow but they're making it flow so in recent years modern medicine has provided us with everything that we know right but uh in terms of hearts they've always tried to make heart pumps and this time is the
2:32 first successful time that it wasn't made as a pump that's crazy explain how it works they say after decades of trial and error among surgeons desperately trying to create a machine that wouldn't break down or cause blood clots and infections two doctors at the texas heart institute developed a device that used whirling rotors to pump blood around the body without a heartbeat does that mean it's better it might be is it like more continuous flow rather than like but there has to be a trade-off though these two doctors first tested the idea in an eight month old calf called abigail removing her heart and successfully replacing it with two centrifugal pumps which circulated the blood through her by every metric we have to analyze patients she's not living technically because the heart's not pumping but she was alive but if you ████ tickle her she's trying to laugh and ████ yeah so she's alive but
3:22 by a health and science concept it's like not alive because no heartbeat right there's no pulse yeah you don't feel a pain there's no pulse but she's technically warm for a ████ extended time so they get more ticklish because of this they get way more ticklish that's crazy so they say after practicing on 38 after practicing on 38 calves two doctors progressed to human trials selecting a 55 year old man called craig lewis who was suffering from amyloidosis a rare autoimmune disease that causes a buildup of abnormal proteins and in turn rapid heart kidney and liver failure what does that mean so lewis heart had become so damaged that doctors gave him about 12 hours to live so he's already gonna die imagine that you just got there in time for hearing ████ let's do this at which point his wife linda suggested something drastic his wife linda said he wanted to live
4:13 and we didn't want to lose them you never know how much time you have but it was worth it i've been reading about these cow hearts can you have one so in march 2011 she approached these two doctors who removed her husband's heart and installed the artificial device wow not a pacemaker no no it's a centrifugal fugal flagger it's a rotary system it's like a pool filter so it looks like this inside whoa whoa that's nuts looks like a tattoo it looks like the that chucky cheese thing it vibrates and you gotta hold hang on yeah this is him post surgery just so you have a face to a name he's alive he's a live post surgery he looks like he's made of wax yeah this is a wax it was just a wax head that's a pretty scary thing madame tassad
5:03 it's like that ████ thing at the front it's probably because of the kidney failure too he's not filtering all his the stuff good enough well post uh operations she said i listened and it was a hum which is amazing he didn't have a pulse she said her husband who worked for the city of houston maintaining the city's uh vast system of waste paper pumps would have appreciated the pulseless heart cobbled together from various materials and the doctor explained uh dacron i don't know the dacrim on the inside and fiberglass impregnated in silicone on the outside so it's pretty much a moderate amount of homemade stuff that puts like what that actual heart is together and he's alive but without a pulse now that's crazy well it worked oh no when it worked oh no it didn't fail it worked successfully however because of his uh autoimmune
5:53 deficiency his other organs failed and then he eventually had to pass damn man but that is pretty crazy but that is still registered as the first successful like heartless human and so we're pretty much bridging entering this age where the science and technology is allowed you know making what countries what country is this in america dang imagine the texas yeah the bill for that well maybe it wasn't so much because if it's a first human trial i'm guessing there might be freebies right because the second you're paying for the service and they ████ up dunzo but if it's kind of like hey we need to try this on a human so he's like you're gonna die anyway so let's try this you know what i'm saying but i don't know maybe there still is a bill because we're in america or maybe because you already had four cert four surgeries on his punch card he that was the fifth surgery like like a boba place yeah he's probably good you get this experimental surgery for free after the surgery he
6:43 did wake up he began to recover he was able to speak and sit up in the chair but yeah his condition i wonder how that affects like if he starts exercising like what happens with his heart like it's able to to maintain that or i'm sure it would yeah like how does it send signals back and forth right like when you're exercising and you and your body knows it needs more oxygen and more nutrients it'll pump harder yeah on purpose yeah does it like centrifuge ████ heart i highly doubt that this dude was getting up sprinting to figure out he should try it though he should have tried yeah tested it my father-in-law has a pacemaker and he he gets nervous while he's exercising or doing really anything so how do how do pacemakers work uh they put it inside of your body and then it works i think it keeps the electrical signal of your heart does that firmware so anytime that's the stupidest ████ i've ever heard about i think yeah technically your heart works like a battery like
7:33 there's positive and negative ions and it's the transfer of that through the membranes that causes it to pump and that's yeah that's what it looks like when it starts to lose the positive ion effect it's when they need to put the sa node or some ████ right so then if if his heart needs a little boosty it like does a charge and like actually just like yeah that's why the like the defibrillators defibrillators it's it's electricity so so like the for the first couple months he didn't he wasn't used to that so all of a sudden his heart would just go like zapping he's like what the ████ oh ████ got it it just jump starts the it needs a signal to keep that is that like when like maybe he was like chilling and then suddenly everything kind of like slowed down so it needed to kind of bring it back up i have no idea yeah it probably felt that this is losing like the charge also if it's low battery it just keeps on hitting him until he replaces it oh ████ like a smoke alarm yeah
8:23 if you guys needed a new heart would you get a new like one of these defibrillators at this age yes at this age i would anything to keep me but if i'm like ████ 80 i'm like ████ it i would i would need a couple more human trials because like this guy he managed he did manage to live for more than a month with a pulseless heart that's that's pretty freaking and the doctors man doctors were able to say the pumps had worked flawlessly and the fact that it was the other organs that failed on them not the heart that's pretty so to be the first human test that's like dude do you think the heart's like dude i'm putting the team in my ████ back can we ████ pick it up somewhere else yeah like it's like a group science project this is ████ up well the heart already gave up it's already out literally even a pacemaker still like on a heart right yeah this new machine yeah only ████ machine which is like that's that's a cyborg so if there were replacements for every other organ that
9:14 failed like there is for the heart which sounds like that's the hardest one then he technically could keep living right yeah technically the future that we're moving towards they're able to keep that function of the blood flow robocop houston reporting for duty he kind of looked like the guy from ████ world cup i mean it's just probably going to be like really really acceptable in a kind of an exponential amount of time because remember i'm assuming the first time like hearing aids were invented or some ████ right that's crazy too or like you see the videos nowadays where it's like uh somebody who's been color blind gets like these pair of glasses and they see like color for the first time yo those videos make me cry just kidding [Laughter] they debunked it no some people were faking them though no because my uh my right hand man at barbell he is colorblind so we got him that for christmas
10:04 and then uh he please faking it for you no he puts it on and he goes so that's what grass looks like and i was just like like you don't think you were just colorblind you don't even know what grass looks like well his reds and his greens are nice so grass looks red to him they look like different shades of like gray you know yeah sometimes colored blind well there's layers to it there's like colorblind there's like color deficiencies right yeah yeah like you saw a fire truck and he goes oh that makes sense why it's that color i knew that one can see it you know just like a lot of things that he did he started cheering because there's just like a lot of things that he didn't understand he had to jump to his own conclusions now it's like i understand why a lot of things are the way they how expensive are those glasses it wasn't that expensive and you saw type this toys holy ████ these things are bright as ████ it's not like children's like primary colors that's so this is crazy like oh my god my magna
10:55 hat's red i thought it was green not gray i thought it was great [Music] you
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